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Epidemiology
Mortality
Race, Sex and age
Modes of Transmission
Pathophysiology
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Vectorial of transmission: in 80% of the cases humans have been infected by vectorial transmission ( via the feces of tritominae)

Transplacental via: the prenatal infection by transplacental passage of trypanosomes from the mother with acute or chronic infection is possible. It has been verified that not infected kids have been born even though the existence of many parasites in the placenta. But on the other hand, it has been found mothers with very low parasitism and the newborn baby with the chagas disease (fever,dystrophy, edema and high parasitism).

Transfusion of infected blood: other important number of infections is produced by the transfusion of blood from donators who ignore that they are infected. There has been some fatal cases but most of them suddenly improve even though the existence of high initial parasitism. The possibility to evolve is conditioned by the infection stock and the receptors immunity.

Breast milk: the transmission of the infection from a mother infected with chagas disease to his child via breast milk is possible. However , it is very rare and some specialist consider that it is a remote risk. Anyway , its advisable that the children of infected mothers not be breast fed.

By accidental contamination in the laboratory: there has been many cases by accidental infection in medical laboratories due to the manipulation of kissing bedbugs, infected animals or biological material from sick people or infected animals. This was the case of Mario Fatala Chaben who died from the infection.

Management of infected animals: people have got infected by skinning wild or semi domestic animals. The trypanosomes have been found in dogs saliva with high parasitism.

Contaminated food (poultry, beef, etc): this is accidental and might happen when eating food that has had contact with feces from infected bedbugs. It is not very frequent and hence not very epidemiologically important.

Source of Information

• Yves Carlier, MD, MSc.
  Chagas Disease (American Trypanosomiasis)
  eMedicine.com, Inc.
  http://www.emedicine.com/med/topic327.htm

Used with permission from eMedicine.com, Inc., 2004. Carlier Y, Luquetti AO, Dias JCP, Truyens C, et al. Chagas Disease (American Trypanosomiasis). eMedicine Journal [serial online]. 2004. Available at: http://www.emedicine.com/med/topic327.htm. Accessed Date (i.e., January 19, 2004).

More Information

The Chagas Disease
Historical Review
      • Dr. Carlos Justiniano Riveiro Chagas (1879-1934)
      • Dr. Salvador Mazza (1886 -1946)
      • Dr. Mario Fatala Chabén (1936-1962)
      • Dr. Oswaldo Cruz (1872-1917)
Medical Information
      • Epidemiology
      • Mortality
      • Race, sex and age.
      • Modes of Transmission
      • Pathophysiology
      • Clinical Information
      • Diagnostic
      • Other Medical Information
Prevention and Control
Frequently Asked Questions

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